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microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes

MicroRNAs (miRNAs) are endogenously expressed small noncoding RNAs. The genomic locations of animal miRNAs are significantly clustered in discrete loci. We found duplication and de novo formation were important mechanisms to create miRNA clusters and the clustered miRNAs tend to be evolutionarily co...

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Bibliografiske detaljer
Udgivet i:Mol Biol Evol
Main Authors: Wang, Yirong, Luo, Junjie, Zhang, Hong, Lu, Jian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989102/
https://ncbi.nlm.nih.gov/pubmed/27189568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw089
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