Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling

We recently reported an immune-modulatory role of conjugated bilirubin (CB) in hepatitis A virus (HAV) infection. During this infection the immune response relies on CD4+ T lymphocytes (TLs) and it may be affected by the interaction of HAV with its cellular receptor (HAVCR1/TIM-1) on T cell surface....

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Corral-Jara, Karla F., Trujillo-Ochoa, Jorge L., Realpe, Mauricio, Panduro, Arturo, Gómez-Leyva, Juan F., Rosenstein, Yvonne, Jose-Abrego, Alexis, Roman, Sonia, Fierro, Nora A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989079/
https://ncbi.nlm.nih.gov/pubmed/27578921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1759027
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