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Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter.

The human neutrophil and monocyte-derived serine protease homologues neutrophil elastase (NE), proteinase 3 (PR3), and azurocidin (AZU) are involved in a variety of immune defense reactions. NE and PR3 assist in the destruction of phagocytosed microorganisms, cleave the important connective-tissue p...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Zimmer, M, Medcalf, R L, Fink, T M, Mattmann, C, Lichter, P, Jenne, D E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49888/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1518849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8215
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