Angiogenin promotes hematopoietic regeneration by dichotomously regulating quiescence of stem and progenitor cells

Regulation of stem and progenitor cell populations is critical in the development, maintenance and regeneration of tissues. Here, we define a novel mechanism by which a niche-secreted ribonuclease, angiogenin (ANG), distinctively alters the functional characteristics of primitive hematopoietic stem/...

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Udgivet i:Cell
Main Authors: Goncalves, Kevin A., Silberstein, Lev, Li, Shuping, Severe, Nicolas, Hu, Miaofen G., Yang, Hailing, Scadden, David T., Hu, Guo-fu
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988404/
https://ncbi.nlm.nih.gov/pubmed/27518564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.06.042
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