Well Differentiated Neuroendocrine Tumors with a Morphologically Apparent High Grade Component: A Pathway Distinct from Poorly Differentiated Neuroendocrine Carcinomas

PURPOSE: Most well-differentiated neuroendocrine tumors (WD-NETs) of the enteropancreatic system are low-intermediate grade (G1,G2). Elevated proliferation demonstrated by either a brisk mitotic rate (>20/10 high power fields) or high Ki67 index (>20%) defines a group of aggressive neoplasms d...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Tang, Laura H., Untch, Brian R., Reidy, Diane L., O'Reilly, Eileen, Dhall, Deepti, Jih, Lily, Basturk, Olca, Allen, Peter J., Klimstra, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988130/
https://ncbi.nlm.nih.gov/pubmed/26482044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0548
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