Traumatic Stress Promotes Hyperalgesia via Corticotropin-Releasing Factor-1 Receptor (CRFR1) Signaling in Central Amygdala

Hyperalgesia is an exaggerated response to noxious stimuli produced by peripheral or central plasticity. Stress modifies nociception, and humans with post-traumatic stress disorder (PTSD) exhibit co-morbid chronic pain and amygdala dysregulation. Predator odor stress produces hyperalgesia in rodents...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuropsychopharmacology
Main Authors: Itoga, Christy A, Roltsch Hellard, Emily A, Whitaker, Annie M, Lu, Yi-Ling, Schreiber, Allyson L, Baynes, Brittni B, Baiamonte, Brandon A, Richardson, Heather N, Gilpin, Nicholas W
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987844/
https://ncbi.nlm.nih.gov/pubmed/27013358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.44
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