Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray

The neuropeptide galanin coexists in rat brain with serotonin in the dorsal raphe nucleus and with noradrenaline in the locus coeruleus (LC), and it has been suggested to be involved in depression. We studied rats exposed to chronic mild stress (CMS), a rodent model of depression. As expected, these...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wang, Peng, Li, Hui, Barde, Swapnali, Zhang, Ming-Dong, Sun, Jing, Wang, Tong, Zhang, Pan, Luo, Hanjiang, Wang, Yongjun, Yang, Yutao, Wang, Chuanyue, Svenningsson, Per, Theodorsson, Elvar, Hökfelt, Tomas G. M., Xu, Zhi-Qing David
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987783/
https://ncbi.nlm.nih.gov/pubmed/27457954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609198113
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