Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray

The neuropeptide galanin coexists in rat brain with serotonin in the dorsal raphe nucleus and with noradrenaline in the locus coeruleus (LC), and it has been suggested to be involved in depression. We studied rats exposed to chronic mild stress (CMS), a rodent model of depression. As expected, these...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wang, Peng, Li, Hui, Barde, Swapnali, Zhang, Ming-Dong, Sun, Jing, Wang, Tong, Zhang, Pan, Luo, Hanjiang, Wang, Yongjun, Yang, Yutao, Wang, Chuanyue, Svenningsson, Per, Theodorsson, Elvar, Hökfelt, Tomas G. M., Xu, Zhi-Qing David
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987783/
https://ncbi.nlm.nih.gov/pubmed/27457954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609198113
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