Depression-like behavior in rat: Involvement of galanin receptor subtype 1 in the ventral periaqueductal gray

The neuropeptide galanin coexists in rat brain with serotonin in the dorsal raphe nucleus and with noradrenaline in the locus coeruleus (LC), and it has been suggested to be involved in depression. We studied rats exposed to chronic mild stress (CMS), a rodent model of depression. As expected, these...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wang, Peng, Li, Hui, Barde, Swapnali, Zhang, Ming-Dong, Sun, Jing, Wang, Tong, Zhang, Pan, Luo, Hanjiang, Wang, Yongjun, Yang, Yutao, Wang, Chuanyue, Svenningsson, Per, Theodorsson, Elvar, Hökfelt, Tomas G. M., Xu, Zhi-Qing David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987783/
https://ncbi.nlm.nih.gov/pubmed/27457954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609198113
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