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Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis

Malignant osteolysis associated with inoperable primary bone tumors and multifocal skeletal metastases remains a challenging clinical problem in cancer patients. Nanomedicine that is able to target and deliver therapeutic agents to diseased bone sites could potentially provide an effective treatment...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yin, Qian, Tang, Li, Cai, Kaimin, Tong, Rong, Sternberg, Rachel, Yang, Xujuan, Dobrucki, Lawrence W., Borst, Luke B., Kamstock, Debra, Song, Ziyuan, Helferich, William G., Cheng, Jianjun, Fan, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987772/
https://ncbi.nlm.nih.gov/pubmed/27457945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603316113
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