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Cytoplasmic dynein binding, run length, and velocity are guided by long-range electrostatic interactions

Dyneins are important molecular motors involved in many essential biological processes, including cargo transport along microtubules, mitosis, and in cilia. Dynein motility involves the coupling of microtubule binding and unbinding to a change in the configuration of the linker domain induced by ATP...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Li, Lin, Alper, Joshua, Alexov, Emil
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987762/
https://ncbi.nlm.nih.gov/pubmed/27531742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31523
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