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Significance of the Melanocortin 1 and Endothelin B Receptors in Melanocyte Homeostasis and Prevention of Sun-Induced Genotoxicity

The membrane bound melanocortin 1 receptor (MC1R), and the endothelin B receptor (ENDBR) are two G-protein coupled receptors that play important roles in constitutive regulation of melanocytes and their response to ultraviolet radiation (UVR), the main etiological factor for melanoma. The human MC1R...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Swope, Viki B., Abdel-Malek, Zalfa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987328/
https://ncbi.nlm.nih.gov/pubmed/27582758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00146
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