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New Therapeutic and Diagnostic Opportunities for Injured Tissue-Specific Targeting of Complement Inhibitors and Imaging Modalities

Despite substantial opportunity and commercial interest in developing drugs that modulate the complement system in a broad range of non-orphan indications, several obstacles remain to be overcome. Among these issues is the biophysical nature of complement proteins, whose circulating levels are typic...

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Detalhes bibliográficos
Publicado no:Semin Immunol
Main Authors: Holers, V. Michael, Tomlinson, Stephen, Kulik, Liudmila, Atkinson, Carl, Rohrer, Bärbel, Banda, Nirmal, Thurman, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987277/
https://ncbi.nlm.nih.gov/pubmed/27282113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2016.05.007
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