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Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds

Current options for aortic valve replacements are non-viable and thus lack the ability to grow and remodel, which can be problematic for paediatric applications. Toward the development of living valve substitutes that can grow and remodel, porcine aortic valve interstitial cells (VICs) were isolated...

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Pubblicato in:J Tissue Eng Regen Med
Autori principali: Wu, Yan, Puperi, Daniel S., Grande-Allen, K. Jane, West, Jennifer L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987276/
https://ncbi.nlm.nih.gov/pubmed/26631842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.2093
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