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From orphan drugs to adopted therapies: Advancing C3-targeted intervention to the clinical stage

Complement dysregulation is increasingly recognized as an important pathogenic driver in a number of clinical disorders. Complement-triggered pathways intertwine with key inflammatory and tissue destructive processes that can either increase the risk of disease or exacerbate pathology in acute or ch...

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Detalhes bibliográficos
Publicado no:Immunobiology
Main Authors: Mastellos, Dimitrios C., Reis, Edimara S., Yancopoulou, Despina, Hajishengallis, George, Ricklin, Daniel, Lambris, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987232/
https://ncbi.nlm.nih.gov/pubmed/27353192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2016.06.013
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