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Catalytic enantioselective total synthesis of (+)-eucomic acid
A catalytic enantioselective synthesis of (+)-eucomic acid is reported. A palladium-catalyzed asymmetric allylic alkylation is employed to access the chiral tetrasubstituted α-hydroxyacid moiety found in the natural product. The protecting group strategy was investigated, and a protecting group mani...
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| Publicado no: | Tetrahedron |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986999/ https://ncbi.nlm.nih.gov/pubmed/27546916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2016.02.059 |
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