Toll Like Receptor 4 Dependent Kupffer Cell Activation and Liver Injury in a Novel Mouse Model of Parenteral Nutrition

Infants with intestinal failure who are parenteral nutrition (PN)-dependent may develop cholestatic liver injury and cirrhosis (PN-associated liver injury: PNALI). The pathogenesis of PNALI remains incompletely understood. We hypothesized that intestinal injury with increased intestinal permeability...

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Опубликовано в: :Hepatology
Главные авторы: El Kasmi, Karim C., Anderson, Aimee L., Devereaux, Michael W., Fillon, Sophie A., Harris, J. Kirk, Lovell, Mark A., Finegold, Milton J., Sokol, Ronald J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986925/
https://ncbi.nlm.nih.gov/pubmed/22120983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25500
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