RANK and RANK ligand expression in primary human osteosarcoma

Receptor activator of nuclear factor kappa-B ligand (RANKL) is an essential mediator of osteoclast formation, function and survival. In patients with solid tumor metastasis to the bone, targeting the bone microenvironment by inhibition of RANKL using denosumab, a fully human monoclonal antibody (mAb...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Bone Oncol
Prif Awduron: Branstetter, Daniel, Rohrbach, Kathy, Huang, Li-Ya, Soriano, Rosalia, Tometsko, Mark, Blake, Michelle, Jacob, Allison P., Dougall, William C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986823/
https://ncbi.nlm.nih.gov/pubmed/27556008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2015.06.002
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