Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila

Caspases are the executioners of apoptosis. Although much is known about their physiological roles and structures, detailed analyses of missense mutations of caspases are lacking. As mutations within caspases are identified in various human diseases, the study of caspase mutants will help to elucida...

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Publicat a:Cell Death Differ
Autors principals: Wu, Y, Lindblad, J L, Garnett, J, Kamber Kaya, H E, Xu, D, Zhao, Y, Flores, E R, Hardy, J, Bergmann, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986642/
https://ncbi.nlm.nih.gov/pubmed/26542461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.144
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