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Genetic characterization of two gain-of-function alleles of the effector caspase DrICE in Drosophila
Caspases are the executioners of apoptosis. Although much is known about their physiological roles and structures, detailed analyses of missense mutations of caspases are lacking. As mutations within caspases are identified in various human diseases, the study of caspase mutants will help to elucida...
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Publicado no: | Cell Death Differ |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986642/ https://ncbi.nlm.nih.gov/pubmed/26542461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.144 |
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