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The handedness-associated PCSK6 locus spans an intronic promoter regulating novel transcripts

We recently reported the association of the PCSK6 gene with handedness through a quantitative genome-wide association study (GWAS; P < 0.5 × 10(−8)) for a relative hand skill measure in individuals with dyslexia. PCSK6 activates Nodal, a morphogen involved in regulating left–right body axis deter...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Shore, Robert, Covill, Laura, Pettigrew, Kerry A., Brandler, William M., Diaz, Rebeca, Xu, Yiwang, Tello, Javier A., Talcott, Joel B., Newbury, Dianne F., Stein, John, Monaco, Anthony P., Paracchini, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986331/
https://ncbi.nlm.nih.gov/pubmed/26908617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw047
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