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Cancer-induced heterogeneous immunosuppressive tumor microenvironments and their personalized modulation

Although recent cancer immunotherapy strategies, including immune-checkpoint blockade (i.e. blocking PD-1, PD-L1 or CTLA-4), have shown durable clinical effects in some (but not all) patients with various advanced cancers, further understanding of human immunopathology, particularly in tumor microen...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Yaguchi, Tomonori, Kawakami, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986236/
https://ncbi.nlm.nih.gov/pubmed/27401477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw030
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