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Hypoxia-elicited impairment of cell wall integrity, glycosylation precursor synthesis, and growth in scaled-up high-cell density fed-batch cultures of Saccharomyces cerevisiae

BACKGROUND: In this study we examine the integrity of the cell wall during scale up of a yeast fermentation process from laboratory scale (10 L) to industrial scale (10,000 L). In a previous study we observed a clear difference in the volume fraction occupied by yeast cells as revealed by wet cell w...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Aon, Juan C., Sun, Jianxin, Leighton, Julie M., Appelbaum, Edward R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986208/
https://ncbi.nlm.nih.gov/pubmed/27527078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0542-3
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