The structural origin of metabolic quantitative diversity

Relationship between structural variants of enzymes and metabolic phenotypes in human population was investigated based on the association study of metabolite quantitative traits with whole genome sequence data for 512 individuals from a population cohort. We identified five significant associations...

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Udgivet i:Sci Rep
Main Authors: Koshiba, Seizo, Motoike, Ikuko, Kojima, Kaname, Hasegawa, Takanori, Shirota, Matsuyuki, Saito, Tomo, Saigusa, Daisuke, Danjoh, Inaho, Katsuoka, Fumiki, Ogishima, Soichi, Kawai, Yosuke, Yamaguchi-Kabata, Yumi, Sakurai, Miyuki, Hirano, Sachiko, Nakata, Junichi, Motohashi, Hozumi, Hozawa, Atsushi, Kuriyama, Shinichi, Minegishi, Naoko, Nagasaki, Masao, Takai-Igarashi, Takako, Fuse, Nobuo, Kiyomoto, Hideyasu, Sugawara, Junichi, Suzuki, Yoichi, Kure, Shigeo, Yaegashi, Nobuo, Tanabe, Osamu, Kinoshita, Kengo, Yasuda, Jun, Yamamoto, Masayuki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985752/
https://ncbi.nlm.nih.gov/pubmed/27528366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31463
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