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Refactoring the λ phage lytic/lysogenic decision with a synthetic regulator

In this work, we explore the refactoring of the circuitry of λ phage by engineering a new‐to‐nature regulator that responds to an ad hoc input signal that behaves orthogonal with respect to the host cell. We tailored a chimeric regulator, termed Qλ, between the CI protein of the λ phage and the BzdR...

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Detalhes bibliográficos
Publicado no:Microbiologyopen
Main Authors: Durante‐Rodríguez, Gonzalo, Mancheño, José Miguel, Díaz, Eduardo, Carmona, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985591/
https://ncbi.nlm.nih.gov/pubmed/26987659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.352
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