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Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy

INTRODUCTION: Pancreatic adenocarcinoma remains one of the most clinically challenging cancers despite an in-depth characterization of the molecular underpinnings and biology of this disease. Recent whole-genome-wide studies have elucidated the diverse and complex genetic alterations which generate...

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Pubblicato in:Expert Opin Ther Targets
Autori principali: Sahin, Ibrahim H, Iacobuzio-Donahue, Christine A, O’Reilly, Eileen M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985526/
https://ncbi.nlm.nih.gov/pubmed/26439702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2016.1094057
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