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Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis

Abelson family kinases (Abls) are key regulators of cell behavior and the cytoskeleton during development and in leukemia. Abl’s SH3, SH2, and tyrosine kinase domains are joined via a linker to an F-actin–binding domain (FABD). Research on Abl’s roles in cell culture led to several hypotheses for it...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Rogers, Edward M., Spracklen, Andrew J., Bilancia, Colleen G., Sumigray, Kaelyn D., Allred, S. Colby, Nowotarski, Stephanie H., Schaefer, Kristina N., Ritchie, Benjamin J., Peifer, Mark
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985262/
https://ncbi.nlm.nih.gov/pubmed/27385341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-05-0292
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