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p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies

Mallory-Denk bodies (MDBs) are hepatocytic protein aggregates found in steatohepatitis and several other chronic liver diseases as well as hepatocellular carcinoma. MDBs are mainly composed of phosphorylated keratins and stress protein p62/Sequestosome-1 (p62), which is a common component of cytopla...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lahiri, Pooja, Schmidt, Volker, Smole, Claudia, Kufferath, Iris, Denk, Helmut, Strnad, Pavel, Rülicke, Thomas, Fröhlich, Leopold F., Zatloukal, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985067/
https://ncbi.nlm.nih.gov/pubmed/27526095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161083
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