載入...
pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug
The objective of this study was to investigate the pH-dependent solubility and dissolution of weakly basic Biopharmaceutical Classification Systems (BCS) class II drugs, characterized by low solubility and high permeability, using carvedilol, a weak base with a pK (a) value of 7.8, as a model drug....
Na minha lista:
| 發表在: | AAPS PharmSciTech |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer US
2015
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4984888/ https://ncbi.nlm.nih.gov/pubmed/26202065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0365-2 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|