Development and Optimization of a Novel Prolonged Release Formulation to Resist Alcohol-Induced Dose Dumping

Alcohol-induced dose dumping is a serious concern for the orally administered prolonged release dosage forms. The study was designed to optimize the independent variables, propylene glycol alginate (PGA), Eudragit RS PO (ERS) and coating in mucoadhesive quetiapine prolonged release tablets 200 mg re...

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Vydáno v:AAPS PharmSciTech
Hlavní autoři: Gujjar, Chaitanya Yogananda, Rallabandi, Balaramesha Chary, Gannu, Ramesh, Deulkar, Vallabh Subashrao
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984876/
https://ncbi.nlm.nih.gov/pubmed/26162975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0358-1
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