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A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection

Rift Valley fever virus (RVFV) is an arbovirus within the Bunyaviridae family capable of causing serious morbidity and mortality in humans and livestock. To identify host factors involved in bunyavirus replication, we employed genome-wide RNA interference (RNAi) screening and identified 381 genes wh...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Harmon, Brooke, Bird, Sara W., Schudel, Benjamin R., Hatch, Anson V., Rasley, Amy, Negrete, Oscar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984662/
https://ncbi.nlm.nih.gov/pubmed/27226375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00543-16
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