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Functional Incompatibility between the Generic NF-κB Motif and a Subtype-Specific Sp1III Element Drives the Formation of the HIV-1 Subtype C Viral Promoter

Of the various genetic subtypes of human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV), only in subtype C of HIV-1 is a genetically variant NF-κB binding site found at the core of the viral promoter in association with a subtype-specific Sp1III motif....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Verma, Anjali, Rajagopalan, Pavithra, Lotke, Rishikesh, Varghese, Rebu, Selvam, Deepak, Kundu, Tapas K., Ranga, Udaykumar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984642/
https://ncbi.nlm.nih.gov/pubmed/27194770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00308-16
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