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Critical Role of the PA-X C-Terminal Domain of Influenza A Virus in Its Subcellular Localization and Shutoff Activity

PA-X is a recently identified influenza virus protein that is composed of the PA N-terminal 191 amino acids and unique C-terminal 41 or 61 residues. We and others showed that PA-X has a strong ability to suppress host protein synthesis via host mRNA decay, which is mediated by endonuclease activity...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Hayashi, Tsuyoshi, Chaimayo, Chutikarn, McGuinness, James, Takimoto, Toru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984632/
https://ncbi.nlm.nih.gov/pubmed/27226377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00954-16
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