Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics

Injection of the LP-BM5 murine leukemia virus into mice causes murine AIDS, a disease characterized by many dysfunctions of immunocompetent cells. To establish whether the disease is characterized by glutathione imbalance, reduced glutathione (GSH) and cysteine were quantified in different organs. A...

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Veröffentlicht in:J Virol
Hauptverfasser: Brundu, Serena, Palma, Linda, Picceri, Giusi Giada, Ligi, Daniela, Orlandi, Chiara, Galluzzi, Luca, Chiarantini, Laura, Casabianca, Anna, Schiavano, Giuditta Fiorella, Santi, Martina, Mannello, Ferdinando, Green, Kathy, Smietana, Michaël, Magnani, Mauro, Fraternale, Alessandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984623/
https://ncbi.nlm.nih.gov/pubmed/27226373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00603-16
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