Galectin-1 is essential to intravenous tolerance induction in experimental autoimmune encephalomyelitis

In experimental autoimmune encephalomyelitis (EAE), intravenous (i.v.) injection of the antigen, myelin oligodendrocyte glycoprotein-derived peptide, MOG(35-55), suppresses disease development, a phenomenon called i.v. tolerance. Galectin-1, an endogenous glycan-binding protein, is upregulated durin...

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Udgivet i:Eur J Immunol
Main Authors: Mari, Elisabeth R., Rasouli, Javad, Ciric, Bogoljub, Moore, Jason N., Conejo-Garcia, Jose R., Rajasagi, Naveen, Zhang, Guang-Xian, Rabinovich, Gabriel A., Rostami, Abdolmohamad
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984530/
https://ncbi.nlm.nih.gov/pubmed/27151444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546212
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