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Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility

PURPOSE: Multiplex genetic testing, including both moderate- and high-penetrance genes for cancer susceptibility, is associated with greater uncertainty than traditional testing, presenting challenges to informed consent and genetic counseling. We sought to develop a new model for informed consent a...

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Detalhes bibliográficos
Publicado no:Genet Med
Main Authors: Bradbury, Angela R., Patrick-Miller, Linda, Long, Jessica, Powers, Jacquelyn, Stopfer, Jill, Forman, Andrea, Rybak, Christina, Mattie, Kristin, Brandt, Amanda, Chambers, Rachelle, Chung, Wendy K., Churpek, Jane, Daly, Mary B., Digiovanni, Laura, Farengo-Clark, Dana, Fetzer, Dominique, Ganschow, Pamela, Grana, Generosa, Gulden, Cassandra, Hall, Michael, Kohler, Lynne, Maxwell, Kara, Merrill, Shana, Montgomery, Susan, Mueller, Rebecca, Nielsen, Sarah, Olopade, Olufunmilayo, Rainey, Kimberly, Seelaus, Christina, Nathanson, Katherine L., Domchek, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983405/
https://ncbi.nlm.nih.gov/pubmed/25297947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2014.134
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