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Omics-based approaches in understanding mechanosensitive endothelial biology and atherosclerosis

Atherosclerosis is a multifactorial disease that preferentially occurs in arterial regions exposed to disturbed blood flow (d-flow). The mechanisms by which d-flow induces atherosclerosis involve changes in the transcriptome, methylome, proteome, and metabolome of multiple vascular cells, especially...

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Bibliographische Detailangaben
Veröffentlicht in:Wiley Interdiscip Rev Syst Biol Med
Hauptverfasser: Simmons, Rachel D., Kumar, Sandeep, Thabet, Salim Raid, Sur, Sanjoli, Jo, Hanjoong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983228/
https://ncbi.nlm.nih.gov/pubmed/27341633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1344
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