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Evaluation of coverage, retention patterns and selectivity of seven liquid chromatographic methods for metabolomics

Liquid chromatography-mass spectrometry (LC-MS)-based metabolomics studies require highly selective and efficient chromatographic techniques. Typically employed reversed-phase (RP) methods fail to target polar metabolites but the introduction of hydrophilic interaction liquid chromatography (HILIC)...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Wernisch, Stefanie, Pennathur, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983217/
https://ncbi.nlm.nih.gov/pubmed/27370688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-9716-4
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