Reciprocal Regulation between Bifunctional miR-9/9(∗) and its Transcriptional Modulator Notch in Human Neural Stem Cell Self-Renewal and Differentiation

Tight regulation of the balance between self-renewal and differentiation of neural stem cells is crucial to assure proper neural development. In this context, Notch signaling is a well-known promoter of stemness. In contrast, the bifunctional brain-enriched microRNA miR-9/9(∗) has been implicated in...

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Опубликовано в: :Stem Cell Reports
Главные авторы: Roese-Koerner, Beate, Stappert, Laura, Berger, Thomas, Braun, Nils Christian, Veltel, Monika, Jungverdorben, Johannes, Evert, Bernd O., Peitz, Michael, Borghese, Lodovica, Brüstle, Oliver
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982985/
https://ncbi.nlm.nih.gov/pubmed/27426040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.06.008
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