2,3,7,8-Tetrachlorodibenzo-p-dioxin Has Both Pro-Carcinogenic and Anti-Carcinogenic Effects on Neuroendocrine Prostate Carcinoma Formation in TRAMP Mice

It is well established that the prototypical aryl hydrocarbon receptor (AHR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) can both cause and protect against carcinogenesis in non-transgenic rodents. But because these animals almost never develop prostate cancer with old age or after carcinogen...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Moore, Robert W., Fritz, Wayne A., Schneider, Andrew J., Lin, Tien-Min, Branam, Amanda M., Safe, Stephen, Peterson, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982706/
https://ncbi.nlm.nih.gov/pubmed/27151233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.04.018
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