The Limonoids TS3 and Rubescin E Induce Apoptosis in Human Hepatoma Cell Lines and Interfere with NF-κB Signaling

Hepatocellular carcinoma (HCC) is extremely resistant towards pharmacological therapy. To date, the multi-kinase inhibitor Sorafenib is the only available therapeutic agent with the potential to prolong patient survival. Using the human hepatoma cell lines HepG2 and Huh7, we analyzed anti-cancer act...

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Vydáno v:PLoS One
Hlavní autoři: Lange, Nicole, Tontsa, Armelle Tsamo, Wegscheid, Claudia, Mkounga, Pierre, Nkengfack, Augustin Ephrem, Loscher, Christine, Sass, Gabriele, Tiegs, Gisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982607/
https://ncbi.nlm.nih.gov/pubmed/27518192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160843
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