DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression

BACKGROUND: The Synapsins (SYN1, SYN2, and SYN3) are important players in the adult brain, given their involvement in synaptic transmission and plasticity, as well as in the developing brain through roles in axon outgrowth and synaptogenesis. We and others previously reported gene expression dysregu...

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Publicado en:BMC Psychiatry
Autores principales: Cruceanu, Cristiana, Kutsarova, Elena, Chen, Elizabeth S., Checknita, David R., Nagy, Corina, Lopez, Juan Pablo, Alda, Martin, Rouleau, Guy A., Turecki, Gustavo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982122/
https://ncbi.nlm.nih.gov/pubmed/27515700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-016-0989-0
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