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DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression

BACKGROUND: The Synapsins (SYN1, SYN2, and SYN3) are important players in the adult brain, given their involvement in synaptic transmission and plasticity, as well as in the developing brain through roles in axon outgrowth and synaptogenesis. We and others previously reported gene expression dysregu...

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Bibliografiska uppgifter
I publikationen:BMC Psychiatry
Huvudupphovsmän: Cruceanu, Cristiana, Kutsarova, Elena, Chen, Elizabeth S., Checknita, David R., Nagy, Corina, Lopez, Juan Pablo, Alda, Martin, Rouleau, Guy A., Turecki, Gustavo
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982122/
https://ncbi.nlm.nih.gov/pubmed/27515700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-016-0989-0
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