The catalytic power of magnesium chelatase: a benchmark for the AAA (+) ATPases

In the first committed reaction of chlorophyll biosynthesis, magnesium chelatase couples ATP hydrolysis to the thermodynamically unfavorable Mg(2+) insertion into protoporphyrin IX (ΔG°′ of circa 25–33 kJ·mol(−1)). We explored the thermodynamic constraints on magnesium chelatase and demonstrate the...

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Udgivet i:FEBS Lett
Main Authors: Adams, Nathan B. P., Brindley, Amanda A., Hunter, C. Neil, Reid, James D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Letters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982103/
https://ncbi.nlm.nih.gov/pubmed/27176620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12214
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