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Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in primary human osteoarthritic chondrocytes

BACKGROUND: Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and neurogenic inflammation. We showed recently that TRPA1 mediates cartilage degradation and joint pain in the MIA-model of osteoarthrit...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Nummenmaa, Elina, Hämäläinen, Mari, Moilanen, Lauri J., Paukkeri, Erja-Leena, Nieminen, Riina M., Moilanen, Teemu, Vuolteenaho, Katriina, Moilanen, Eeva
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982008/
https://ncbi.nlm.nih.gov/pubmed/27515912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1080-4
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