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‘2A‐Like’ Signal Sequences Mediating Translational Recoding: A Novel Form of Dual Protein Targeting

We report the initial characterization of an N‐terminal oligopeptide ‘2A‐like’ sequence that is able to function both as a signal sequence and as a translational recoding element. Owing to this translational recoding activity, two forms of nascent polypeptide are synthesized: (i) when 2A‐mediated tr...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Roulston, Claire, Luke, Garry A., de Felipe, Pablo, Ruan, Lin, Cope, Jonathan, Nicholson, John, Sukhodub, Andriy, Tilsner, Jens, Ryan, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons A/S 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981915/
https://ncbi.nlm.nih.gov/pubmed/27161495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12411
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