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Dissociable effects of the prodrug phendimetrazine and its metabolite phenmetrazine at dopamine transporters
Phendimetrazine (PDM) is a clinically available anorectic and a candidate pharmacotherapy for cocaine addiction. PDM has been hypothesized to function as a prodrug that requires metabolism to the amphetamine-like monoamine transporter substrate phenmetrazine (PM) to produce its pharmacological effec...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981850/ https://ncbi.nlm.nih.gov/pubmed/27514281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31385 |
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