In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into the nascent parasitophorous vacuole. These GRAs are belie...

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Détails bibliographiques
Publié dans:mBio
Auteurs principaux: Nadipuram, Santhosh M., Kim, Elliot W., Vashisht, Ajay A., Lin, Andrew H., Bell, Hannah N., Coppens, Isabelle, Wohlschlegel, James A., Bradley, Peter J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981711/
https://ncbi.nlm.nih.gov/pubmed/27486190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00808-16
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