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Successful treatment of ibrutinib-associated central nervous system hemorrhage with platelet transfusion support

Ibrutinib is a novel targeted therapy for B-cell malignancies. Hemorrhagic events were reported in the original trials, however the mechanism of bleeding is just being elucidated. Recent studies have demonstrated platelet dysfunction as a mechanism of bleeding. Currently we report two patients who d...

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Publicado en:Stem Cell Investig
Autores principales: Seiter, Karen, Stiefel, Michael F., Barrientos, Jacqueline, Shaikh, Azfar, Ahmed, Nasir, Baskind, Paul, Liu, Delong
Formato: Artigo
Lenguaje:Inglês
Publicado: AME Publishing Company 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981699/
https://ncbi.nlm.nih.gov/pubmed/27583253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.06.08
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