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Family-based Rare Variant Association Analysis: a Fast and Efficient Method of Multivariate Phenotype Association Analysis

MOTIVATION: Family-based designs have been repeatedly shown to be powerful in detecting the significant rare variants associated with human diseases. Furthermore, human diseases are often defined by the outcomes of multiple phenotypes, and thus we expect multivariate family-based analyses may be ver...

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Bibliographische Detailangaben
Veröffentlicht in:Genet Epidemiol
Hauptverfasser: Wang, Longfei, Lee, Sungyoung, Gim, Jungsoo, Qiao, Dandi, Cho, Michael, Elston, Robert C, Silverman, Edwin K, Won, Sungho
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981535/
https://ncbi.nlm.nih.gov/pubmed/27312886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21985
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