Biphenotypic Sinonasal Sarcoma: an Expanded Immunoprofile Including Consistent Nuclear Beta-Catenin Positivity and Absence of SOX10 Expression

Biphenotypic sinonasal sarcoma (BSNS) is a recently recognized low-grade sarcoma that exhibits both neural and myogenic differentiation. This unique dual phenotype stems from recurrent rearrangements in PAX3, a transcription factor that promotes commitment along both lineages. While identification o...

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Udgivet i:Hum Pathol
Main Authors: Rooper, Lisa M., Huang, Shih-Chiang, Antonescu, Cristina R., Westra, William H., Bishop, Justin A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981530/
https://ncbi.nlm.nih.gov/pubmed/27137987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2016.04.009
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